James Hicks, Ph.D.

Research Professor, Biological Sciences

Dr. Hicks is a pioneer of single cell genomics and translational cancer research with a focus in breast and prostate cancer. He is focused on the development and implementation of high content single cell assays to understand the spatial and temporal evolution of cancer in the human body.  He is an experienced academic researcher and corporate entrepreneur with a long history of translating science into useful products having published over one hundred scientific papers and patents, as well as having started a number of companies.

His ground breaking developments in single cell genomics have enabled the routine whole genome analysis of individual cells that he initially applied to solid tumor biopsies until, in 2012, he started work with Dr. Kuhn to utilize the combined technologies as a high density single cell analysis framework across all solid and liquid biopsies. This work is rapidly becoming the standard in research focused on the spatial and temporal evolution of cancer.

His future work at The Bridge@USC will expand on this theme to understand a broad range of systemic diseases including cancer, cardiovascular disease, rheumatoid arthritis and diabetes, which all suffer from similar challenges of poorly understand disease evolution under natural and therapeutic pressures.

Dr. Hicks is a geneticist who trained initially at the University of Oregon and built his career with research and faculty appointments at Cornell University and Cold Spring Harbor Laboratories, as well as a broad range of industrial leadership positions. He is Professor (Research) of Biological Sciences in the USC Dornsife College of Letters, Arts and Sciences. In addition to his appointment at The Bridge@USC, Hicks is also an adjunct professor of medicine at the Charles University of Prague.

More information about James Hicks’s research.