Judith Kribelbauer is the Gabilan Assistant Professor of Biological Sciences. Her research focuses on developing high-throughput techniques to answer fundamental questions on human gene regulation. Dr. Kribelbauer uses a synthetic genomics approach, creating minimal gene regulatory modules that allow us to gain detailed insight on the sophisticated mechanisms that control the expression of native genes in both healthy and disease contexts. The ultimate goal of her lab is to develop new design strategies to improve expression control of gene therapies.
Dr. Kribelbauer received a B.S. in Chemistry from the Ruprecht Karl University in Heidelberg, Germany, where she worked on the structural basis of the signal recognition particle targeting complex in Dr. Irmgard Sinning’s lab. She then moved on to Columbia University, NY, where she joined the labs of Drs. Harmen Bussemaker and Richard Mann, receiving her PhD in 2018. While at Columbia she was supported by a Howard Hughes Medical Institute international student fellowship to develop high-throughput tools to probe how transcription factor binding responds to epigenetic DNA modifications and protein-protein interactions. She then worked as both an EMBO and Marie-Curie Postdoctoral Fellow in the lab of Dr. Bart Deplancke at EPFL in Switzerland, where she devised computational and experimental strategies to investigate how transcription factors create cooperative enhancer environments and how they mediate enhancer-promoter communication.